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The Pomeranz–Fritsch reaction, also named Pomeranz–Fritsch cyclization, is a name reaction in the organic chemistry. It is named after Paul Fritsch (1859–1913) and Cäsar Pomeranz (1860–1926). In general it is a synthesis of isoquinoline.〔 == General Reaction Scheme == The reaction below shows the acid-promoted synthesis of isoquinoline from benzaldehyde and a 2,2-dialkoxyethylamine. Various alkyl groups, e.g. methyl and ethyl groups, can be used as substituent R. In the archetypical reaction sulfuric acid was used as proton donor, but Lewis acids such as trifluoroacetic anhydride and lanthanide triflates have been used occasionally.〔〔〔 Later, a wide range of diverse isoquinolines were successfully prepared.〔 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Pomeranz–Fritsch reaction」の詳細全文を読む スポンサード リンク
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